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2021
Nießing, B., Kiesel, R., Herbst, L., and Schmitt, R. H. (2021). Techno-Economic Analysis of Automated iPSC Production. Process. Band 9. Heft 2, 2021.
Toledo, M. A. S., Gatz, M., Sontag, S., Gleixner, K. V., Eisenwort, G., Feldberg, K., Hamouda, A. E. I., Kluge, F., Guareschi, R., Rossetti, G., Sechi, A. S., Dufva, O. M. J., Mustjoki, S. M., Maurer, A., Schüler, H. M., Goetzke, R., Braunschweig, T., Kaiser, A., Panse, J., Jawhar, M., Reiter, A., Hilberg, F., Ettmayer, P., Wagner, W., Koschmieder, S., Brümmendorf, T. H., Valent, P., Chatain, N., and Zenke, M. (2021)
Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.
Blood 137, 2070-2084. with Commentary by Dorrance, A. „Mast“ering drug discovery with iPSCs. Blood 137, 1993-1994.
2020
Lampert, A., Bennett, D. L., McDermott, L. A., Neureiter, A., Eberhardt, E., Winner, B., and Zenke, M. (2020)
Human sensory neurons derived from pluripotent stem cells for disease modelling and personalized medicine.
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Elanze, A., Nießing, B., Langendoerfer, C., Rippel, O., Piotrowski, T., Schenk, F., Kulik, M., Peitz, M., Breitkreuz, Y., Jung, S., Wanek, P., Stappert, L., Schmitt, R. H., Haupt, S., Zenke, M., König, N., and Brüstle, O. (2020).
The StemCellFactory: A Modular System Integration for Automated Generation and Expansion of Human Induced Pluripotent Stem Cells. Frontiers in Biotechnology and Biology.
2019
Meents, J. E., Bressan, E., Sontag, S., Foerster, A., Hautvast, P., Rösseler, C., Hampl, M., Schüler, H., Goetzke, R., Chi Le, T. K., Kleggetveit, I. P., Le Cann, K., Kerth, C., Rush, A. M., Rogers, M., Kohl, Z., Schmelz, M., Wagner, W., Jørum, E., Namer, B., Winner, B., Zenke, M., and Lampert, A. (2019).
The role of Nav1.7 in human nociceptors: insights from human iPS cell-derived sensory neurons of erythromelalgia patients. Pain 160, 1327-1341.
2018
Jung, S., Ochs, J., Kulik, M., König, N., Schmitt, R. H. (2018).
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2017
Kulik, M; Ochs, J; König, N; McBeth, C; Sauer-Budge, A; Sharon, A; Schmitt, R: Parallelization in Automated Stem Cell Culture. In: Procedia CIRP, 65, ISSN 2212-8271, S. 242–247, 2017
Roese-Koerner, B; Stappert, L, Brüstle, O: Notch/Hes signaling and miR-9 engage in complex feedback interactions controlling neural
progenitor cell proliferation and differentiation Neurogenesis. 4(1):e1313647, DOI: 10.1080/23262133.2017.1313647,
2017
Jungverdorben, J; Till, A; Brüstle, O: Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on
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Haubenreich, C; Lenz, M; de Boni, L; Walter, J; Schuppert, A; Koch, P; Zenke, M; Brüstle, O: Epigenetic and transcriptional alterations in human neural stem cells subjected to reprogramming and subsequent redifferentiation. In: manuscript in preparation, 2017
Sontag, S; Forster, M; Sere, K; Zenke, M: Differentiation of Human Induced Pluripotent Stem Cells (iPS Cells) and Embryonic Stem Cells (ES Cells) into Dendritic Cell (DC) Subsets. In: BioProtoc 7, e241, 2017
Sontag, S; Forster, M; Qin, J; Wanek, P; Mitzka, S; Schuler, H M; Koschmieder, S; Rose-John, S; Sere, K; Zenke, M: Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells. In: Stem Cells 35 898-908, 2017
2016
Kulik, M; Elanzew, A; Haupt, S; Wanek, P; Ochs, J; König, N; Zenke, M; Brüstle, O; Schmitt, R: Novel platform for fully automated generation and expansion of highly standardized iPS cells. In: Journal of Biotechnology 84, 2016, 231 Supplement , ISSN 0168-1656 , S. 33 - 34
Schenk, F; Brill, N; Marx, U; Hardt, D; König, N; Schmitt, R: High-speed microscopy of continuously moving cell culture vessels. In: Scientific Reports, 2016, 6, ISSN 2045-2322, S. 34038
Roese-Koerner, B; Stappert, L; Berger, T; Braun, N C; Veltel, M; Jungverdorben, J; Evert, B O; Peitz, M; Borghese, L; Brüstle, O: Reciprocal regulation between bifunctional miR-9/9* and its transcriptional modulator Notch in human neural stem cell self-renewal and differentiation. In: Stem Cell Reports, 2016, 7(2):207-19. doi:10.1016/j.stemcr.2016.06.008. Epub, 14 Jul 2016.
Falk, A; Heine, V M; Harwood, A J; Sullivan, P F; Peitz, M; Brüstle, O; Shen, S; Sun, Y M; Glover, J C; Posthuma, D; Djurovic, S: Modeling psychiatric disorders: from genomic findings to cellular phenotypes. In: Mol Psychiatry, 2016, 21(9):1167-79. doi: 10.1038/mp.2016.89. Epub, 31 Mai 2016
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2015
Elanzew, A; Sommer, A; Pusch-Klein, A; Brüstle, O; Haupt, S: A reproducible and versatile system for the dynamic expansion of human pluripotent stem cells in suspension. In: Biotechnol
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Friedrichs, S; Malan, D; Voss, Y; Sasse, P: Scalable Electrophysiological Investigation of iPS Cell-Derived Cardiomyocytes Obtained by a Lentiviral Purification Strategy. In: J. Clin.
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Hadenfeld, M: StemCellFactory: Eine Produktionsstraße für Stammzellen für die Wirkstoffentwicklung. In: Exzellenz NRW, Das Clustermagazin Nordrhein-Westfalen, Ausgabe 9, 2015
Lenz, M; Goetzke, R; Schenk, A; Schubert, C; Veeck, J; Hemeda, H; Koschmieder, S; Zenke, M; Schuppert, A; Wagner, W: Epigenetic biomarker to support classification into pluripotent and
non-pluripotent cells. In: Scientific Reports, Volume 5, Article Number:8973, 2015
Schenk, FW; Kulik, M; Schmitt, R: Metrology-based quality and process control in automated stem cell production. In: Messtechnikbasierte Qualitätskontrolle und Prozesssteuerung in der
automatisierten Stammzellproduktion. tm - Technisches Messen, Jun Volume 82, Issue 6, 309–316, 2015
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FU; Greber, B: Universal Cardiac Induction of Human Pluripotent Stem Cells in 2D and 3D formats - Implications for In-Vitro Maturation. In: Stem Cells, 2015
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2014
Frobel, J; Hemeda, H; Lenz, M; Abagnale, G; Joussen, S; Denecke, B; Saric, T; Zenke, M; Wagner, W: Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem
cells. In: Stem Cell Reports, 3(3):414-22, 9 Sep 2014
Haupt, S: Fabrik zur Stammzellproduktion. In: Interviewbeitrag, Transkript Nr.9/2014 – 20. Jahrgang, 2014
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Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling. In: Stem Cell Rev., 13 Nov 2014
Qin, J; Sontag, S; Lin, Q; Mitzka, S; Leisten, I; Schneider, RK; Wang, X; Jauch, A; Peitz, M; Brüstle, O; Wagner, W; Zhao, RC; Zenke, M: Cell fusion enhances mesendodermal
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2013
Koch, CM; Reck, K; Shao, K; Lin, Q; Joussen, S; Ziegler, P; Walenda, G; Drescher, W; Opalka, B; May, T; Brümmendorf, T; Zenke, M; Saric, T; Wagner, W: Pluripotent stem cells escape from
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Lenz, M; Schuldt, BM; Müller, F-J; Schuppert, A: PhysioSpace: Relating gene expression experiments from heterogeneous sources using shared physiological processes. In: PLoS ONE,
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2012
Haupt, S; Grützner, J; Thier, M C; Kallweit, T; Rath, B H; Laufenberg, I; Forgber, M; Eberhardt, J; Edenhofer, F; Brüstle, O: Automated selection and harvesting of pluripotent stem cell
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Hemeda, H; Wagner, W: Tracking of Replicative Senescence in Mesenchymal Stem Cells by Colony Forming Unit Assays. In: Methods Mol. Biol., 2012
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